About
ALPHA IVF & WOMEN’S SPECIALISTS
The IVF Centre that is complete with world-class success rates and expertise
Founded in 2011, Alpha IVF & Women’s Specialists is a world’s leading fertility centre with some of the most recognisable figures in the field of fertility treatment that have been responsible for some of the most important fertility developments and breakthrough on a local, regional, and global level.
Nestled in the bustling township of Kota Damansara, Alpha IVF undergone a complete transformation in 2019 into a 26221 square feet purpose-built fertility centre and was officially opened by her majesty, the queen of Malaysia. The centre is fully equipped with latest revolutionary technologies for performing a full suite of advanced IVF treatment options including Preimplantation Genetic Testing, Artificial Intelligence (AI) - Enhanced Embryo Selection Program, OVA – PRP, Endo – PRP, Saviour Sibling Program, egg donation program, egg freezing with close to a 100-per cent post-thaw survival rate, just to name a few.
With strong research and innovative fertility treatment procedures that continue to make inroads, the centre has successfully culminated numerous world’s firsts, Malaysia and Singapore’s f irsts fertility achievements, published more than 200 scientific papers including peer review papers, as well as achieving high IVF success rates up to 82.9%* which is comparable to top IVF centres around the world.
Alpha IVF is a certified fertility centre under RTAC – an accreditation issued to assisted reproductive technology units or fertility centres that meet the code of practice developed by the Reproductive Technology Accreditation Committee (RTAC) of the Fertility Society of Australia (FSA) and is also an elite member of MHTC (Malaysia Healthcare Travel Council).
Alpha IVF was accorded the Frost & Sullivan’s 2018 Malaysia Fertility Centre of the year for leadership, technological innovation, customer service and strategic product development as well as Asia Pacific Fertility Service Provider of the year 2019, Fertility (IVF) Service Provider of the Year in Asia Pacific 2020 and Best Fertility – Excellence in Technology Service Provider of the Year in Asia Pacific 2020, as well as Asia Pacific Fertility Service Provider of the year for year 2021, 2022 and 2023 by Global health Asia-Pacific Awards.
In the tradition of FIRSTS, we at ALPHA IVF are committed to putting our patients and their fertility needs as our 1st priority. We treat every couple individually and tailor make a treatment programme that caters to their specific needs, enabling our patients to fully realise their potential for parenthood.
*Lee CSS, Low SY. Oral presentation at the 24th Asian & Oceanic Congress of Obstetrics & Gynaecology, 3-6 June 2015, Kuching, Sarawak, Malaysia
Contents
About Alpha IVF & Women’s Specialists
2
Why Choose Alpha IVF & Women’s Specialists
4
Our Doctors
6
Alpha IVF Group’s International Scientific Board
8
Alpha IVF’s (Kuala Lumpur) Embryologists, Geneticists & Scientists
10
Nurses & Counsellors
12
Fertility Treatments
13
Techniques & Technologies
14
Documented Success Rates
20
Our Fertility Achievements
24
Awards
25
Your 1st Visit to Alpha IVF & Women’s Specialists
26
Talk to Us
27
Our Doctors
Dato’ Dr. Colin Lee Soon Soo
FRCOG (UK), MBBS (AUS], MMED (S’PORE) Consultant Fertility Specialist & Gynaecologist Medical Director
The name of Dato Dr. Colin Lee is no stranger in the field of fertility treatment in the international fertility fraternity.
Dato’ Dr Colin Lee Soon Soo set up his new fertility centre, Alpha Fertility Centre, in 2011 which is now better known as Alpha IVF & Women’s Specialists. He was also the founder and medical director of Tropicana Medical Centre, TMC Fertility Centre and Damansara Fertility Centre.
Dato’ Dr. Colin Lee leads the team at Alpha IVF & Women’s Specialists with the mission to enable every couple to fully realise their potential for parenthood.
The core tenet of this work is reflected in the professional standard we are adopting in Alpha IVF, as well as IVF success rates that are comparable with top IVF centres around the world.
Alpha IVF Group’s
International Scientific Board
Emeritus Professor Dr. Bruno Lunenfeld
Dr. John Keith
World-wide pioneer in the development and deployment of human menopausal gonadotrophins (HMG) for the treatment of infertility (since 1961). All patients undergoing IVF who use HMG such as Gonal-F, Puregon, Menopur and Humog are indebted to this towering pioneer of fertility treatment.
Co-created the world’s 1st structured training manual for embryologists. Dr Keith also co created the world’s first professional body for embryologists, that is, the Association of Clinical Embryologists (ACE).
Emeritus Professor Dr. Alan Trounson
Dr. Michelle Perugini
Pioneered the world’s first human IVF pregnancy (1973). He was also the first in the world to achieve a pregnancy following freeze thaw of embryos and pioneered early development in cryopreservation of embryos and blastocysts.
Prof Dr. Alan Trounson is also a pioneer in embryo biopsy and In-Vitro Maturation (IVM).
Co-founder & CEO of Presagen, co-created Presagen’s first product Life Whisperer, a suite of applications that use AI for embryo assessment to improve pregnancy outcomes in IVF.
An avid supporter of the AI and women’s health sectors globally, and the Winner of the 2021 Women in AI (WAI) Healthcare Award.
Nurses & Counsellors
Our fertility trained nurses will walk alongside with you and are ever ready to be your primary contact to guide and support you throughout your journey with us.
Customised
Fertility Treatments
• Ovulation Induction
• Intra Uterine Insemination (IUI)
• In Vitro Fertilisation (IVF)
• Intra-Cytoplasmic Sperm Injection (ICSI)
• Preimplantation Genetic Testing (PGT) :
• PGT-A: Aneuploidy, formerly called PGS
(to screen all 23 pairs of chromosomes)
• PGT-M for Monogenic disorders
(to look for specific disorders that you and your partner are carriers of)
• PGT-SR for Chromosomal Structural Rearrangement
• PGT-HLA for definitive HLA matching
(to look for an HLA-matched embryo for an affected child you already have)
• Blastocysts Transfer Programme
• Egg / Embryo / Sperm Freezing
• Endometrium Receptivity Analysis (ERA)
• Endometrial Microbiome Metagenomic Analysis (EMMA)
• Analysis of Infectious Chronic Endometritis (ALICE)
• Savior Sibling Programme (PGT - HLA)
• X & Y Sperm Sorting
• Advanced Reproductive Surgery
• General O&G
• Ova-PRP - Ovarian Rejuvenation
• Endo-PRP - Endometrium Rejuvenation
• Artificial Intelligence (AI) - Enhanced Embryo Selection
3 • Embryoscope+®Time Lapse Monitoring System
As the first IVF centre in Malaysia that used time lapse system, Alpha IF has now upgraded to EmbryoScope+® Time Lapse System to carefully monitor and this cutting-edge system combines each incubator, high resolution camera and computer software to automatically take images of each developing embryo every 10 minutes. These images can be reviewed at any time by our highly trained embryologists without removing the embryos from the incubator, hence providing undisturbed culture conditions, and improves embryo selection by selecting the most viable embryo for transfer.
4• Blastocyst Transfer Programme
World Class Success Rate 79.5%*
Pregnancy rate from transferring a single good graded euploid blastocyst.
Good graded euploid blastocyst transfer
* Lee C.S.S., Low S.Y., Lim Y.X., Keith J (Alpha Fertility Centre). Vitrified-warmed good graded euploid blastocysts aged < 120hours at the time of transfer yield superior clinical pregnancy and implantation rates. Presented at 24th Congress of the Obstetrical and Gynecological Society of Malaysia, 2 - 5th June 2016, Kuala Lumpur, Malaysia
Since July 2013, Alpha IVF & Women’s Specialists had started using a new embryo freezing and thawing method (Cryotec Method, Japan) and it had led us to achieve a 100% post-thaw survival rate resulting in high clinical pregnancy rates. The chart on the right shows the clinical outcome of Alpha IVF & Women’s Specialists’s frozen-thawed cycles from July 2013 to December 2015*
Donor Egg Programme
Egg donation makes pregnancy possible for women who might not otherwise be able to get pregnant using their own eggs. Alpha IVF & Women’s Specialists has one of the best egg donation programmes in Malaysia. Regardless of fertility history, all recipients of all ages have almost an equal chance of success.
* Leong, WY; Lee, CSS; Low SY (Alpha Fertility Centre). Oocyte donation outcome at Alpha International Fertility Centre. An International Journal of Obstetrics & Gynaecology 2012;119(S1):PP. 137. Presented at the 10th Royal College of Obstetricians & Gynaecologists International Scientific Congress, 5-8 June 2012, Sarawak, Malaysia.
Achievements
1• Live birth in an ERA patient with a receptive endometrium at 190+/- 3 hours (Day 8) of progesterone. (Reproductive BioMedicine Online. 2022:45:51-52;13th ALPHA BIENNIAL CONFERENCE, Alpha Conference, 6th - 9th October 2022)
2• Live birth following frozen embryo transfer of a blastocyst selected using artificial intelligence (AI). (28th International Congress of the Obstetrical & Gynaecological Society of Malaysia, 23-25 July 2021) (South-East Asia 1st)
3• 100% post-warmed survival rate for 6,059 embryos in Alpha IVF. (28th International Congress of the Obstetrical & Gynaecological Society of Malaysia, 23-25 July 2021)
4• Live birth in an ERA patient with a receptive endometrium at 85+/- hours post-progesterone. (10th Virtual Congress Asia Pacific Initiative on Reproduction (ASPIRE),30 April-2 May 2021)
5• Live births following day 7 blastocyst transfers at Alpha IVF. (10th Virtual Congress Asia Pacific Initiative on Reproduction (ASPIRE), 30 April-2 May 2021)
6• Successful pregnancies following transfer of blastocysts derived from delayed-intracytoplasmic sperm injection (delayed-ICSI). (36 Virtual Annual Meeting of European Society of Human Reproduction and Embryology (ESHRE), 05-08 July 2020)
7• Demonstrated that blastocysts arising from Day1-Mll oocytes have the same euploidy rate as Day0-MIl oocytes from the same cycle and therefore should not be discarded. This will increase the number of euploid blastocysts available for embryo transfer. (9th Congress of Asia Pacific Initiative on Reproduction (ASPIRE), 3-5 May 2019, Central, Hong Kong.)
8• Demonstrated that repeated vitrification and repeated warming procedures have no detrimental effect on blastocyst survival and pregnancy outcome. (18th International Conference on Preimplantation Genetic Diagnosis, Geneva, Switzerland, 2019)
9• Savior Sibling Programme for monogenic disorders using direct HLA typing on the embryos from the same biopsy sample used for PGT testing (AICOG, Bengaluru, 8-12 Jan 2019)
10• Demonstrated that administration of Clotrimazole prior to Frozen Embryo Transfer [FET] Cycles may improve implantation rate. (16th International Conference on Preimplantation Genetic Diagnosis, Valencia, Spain, 2017)
11• Demonstrated that combining a Day 5 and a Day 6 Blastocyst results in very high pregnancy rates (Clinical Pregnancy Rate: 71.4%, Implantation Rate: 46.4%). (6th Congress of the Asia Pacitic Initiative on Reproduction, Jakarta, Indonesia, 8-10th April 2016)
12• Successful live birth following frozen embryo transfer of a 1PN embryo after PGD-MaCGH analysis. (14th International Conference on PGD, Chicago, USA 2015)
13• Demonstrated that embryos derived from conventional IF have lower aneuploidy rates compared to embryos derived from ICSI. (13th International Conference on PGD. Canterbury, UK, May 2014)
14• Demonstrated similar euploidy rates among Day 3 OPN, 1PN and 2PN embryos using MaCGH analysis. (12th International Conference on PGD. Istanbul, Turkey, May 2013)
15• Reported successful pregnancy following the use of freeze- thawed sperm, freeze-thawed eggs, and freeze-thawed embryos. (10th Royal College of O&G International Scientific Congress, June 2012)
16• Successful pregnancy and delivery in a patient with Mullerian Dysgenesis la woman born without a vaginal. (Reproductive BioMedicine Online, Vol 24, Issue 5, Pages 547-549), (May 2012]
17• Successful pregnancy and delivery following PGD-CGH diagnosis of chromosome inversion with fresh transfer. (11th International Conference on PGD, May 17th-19th 2012. Austria)
18• PRP treatment for Ashermann’s Syndrome with resulting successful pregnancy and delivery. (2010)
19• Demonstrated that an older uterus (about 40 years old) achieves similar pregnancy rates compared to uterus less than 30 years old. (Reproductive Biomedicine Online, 16[SUPPI2]:S37-38 2008)
20• Reported delivery following the salvage of a presumably abnormal embryo. (7th Congress of PGDIS. Melbourne, Australia 13-15 June 2007)
21• Developed a mathematical formula to guide doctors on appropriate quantum of ovarian drilling. (Life, Issue 9, Page 14-16, 2007)
22• Demonstrated the value of tube rinsing in oocyte recovery procedure. (14th World Congress on IVF and 3rd World Congress on IVM. Montreal, Canada, 2007)
23• Demonstrated the importance of embryo transfer duration on pregnancy outcome. (14th World Congress on IVF and 3rd World Congress on IVM. Montreal, Canada, 2007) • Invented a womb mimicking machine called SHOOGLE” that aims to improve circulation of nutrients to embryos.
For list of other achievements, Please refer to our website at .

Your 1st Visit
to Alpha IVF & Women’s
Specialists
Fertility Assessment
The initial crucial step in assessing your fertility potential and concerns will usually involve a fertility assessment on both you and your partner.
This assessment typically involves a thorough medical history review, physical examinations, and reproductive function tests. By analysing factors such as sperm quality, ovarian reserve, and reproductive anatomy, the doctor can identify any underlying issues or potential challenges.
Tips:
Your Treatment
At Alpha IVF, we cater to your specific needs by providing a treatment programme that is tailor-made just for you.
Upon commencement of treatment, a combination of prescription drugs and a complete drugs administration sheet will be given to you. Other drugs may be introduced in the treatment programme depending on individual requirements.
Based on this comprehensive evaluation, the doctor can then gain valuable insights and offer appropriate recommendations and design a personalised treatment plan that suits the specific needs and conditions of the couple.
Talk to Us
Making an appointment to see a fertility specialist may seem like a big step. Considering that there many misconceptions associated with fertility issues, we know how difficult it is for couples to take the first step in crossing that bridge. Talk to us directly and see how we can help to improve your overall experience and pregnancy outcomes. Alpha IVF has many treatment options to help your dreams of building a family come true.
Contact our softwar:
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