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ALPHA IVF & WOMEN’S SPECIALISTS INFORMATION BOOKLET

About

ALPHA IVF & WOMEN’S SPECIALISTS

The IVF Centre that is complete with world-class success rates and expertise


Founded in 2011, Alpha IVF & Women’s Specialists  is a world’s leading fertility centre with some of the  most recognisable figures in the field of fertility  treatment that have been responsible for some  of the most important fertility developments and  breakthrough on a local, regional, and global  level. 


 Nestled in the bustling township of Kota  Damansara, Alpha IVF undergone a complete  transformation in 2019 into a 26221 square  feet purpose-built fertility centre and was  officially opened by her majesty, the queen of  Malaysia. The centre is fully equipped with latest  revolutionary technologies for performing a full  suite of advanced IVF treatment options including  Preimplantation  Genetic  Testing,  Artificial  Intelligence (AI) - Enhanced Embryo Selection  Program, OVA – PRP, Endo – PRP, Saviour Sibling  Program, egg donation program, egg freezing  with close to a 100-per cent post-thaw survival  rate, just to name a few. 


 With strong research and innovative fertility  treatment procedures that continue to make  inroads, the centre has successfully culminated  numerous world’s firsts, Malaysia and Singapore’s  f  irsts fertility achievements, published more  than 200 scientific papers including peer review  papers, as well as achieving high IVF success  rates up to 82.9%* which is comparable to top  IVF centres around the world.

Alpha IVF is a certified fertility centre under RTAC – an accreditation issued to assisted reproductive  technology units or fertility centres that meet the  code of practice developed by the Reproductive  Technology Accreditation Committee (RTAC) of  the Fertility Society of Australia (FSA) and is also  an elite member of MHTC (Malaysia Healthcare  Travel Council).


 Alpha IVF was accorded the Frost & Sullivan’s  2018 Malaysia Fertility Centre of the year for  leadership, technological innovation, customer  service and strategic product development as  well as Asia Pacific Fertility Service Provider of  the year 2019, Fertility (IVF) Service Provider of  the Year in Asia Pacific 2020 and Best Fertility –  Excellence in Technology Service Provider of the  Year in Asia Pacific 2020, as well as Asia Pacific  Fertility Service Provider of the year for year 2021,  2022 and 2023 by Global health Asia-Pacific  Awards. 


 In the tradition of FIRSTS, we at ALPHA IVF are  committed to putting our patients and their  fertility needs as our 1st priority. We treat every  couple individually and tailor make a treatment  programme that caters to their specific needs,  enabling our patients to fully realise their potential  for parenthood.


*Lee CSS, Low SY. Oral presentation at the 24th Asian & Oceanic Congress  of Obstetrics & Gynaecology, 3-6 June 2015, Kuching, Sarawak, Malaysia


Contents

 About Alpha IVF & Women’s Specialists

2

Why Choose Alpha IVF & Women’s Specialists

4

Our Doctors

6

Alpha IVF Group’s International Scientific Board

8

Alpha IVF’s (Kuala Lumpur) Embryologists, Geneticists & Scientists

10

Nurses & Counsellors

12

Fertility Treatments

13

Techniques & Technologies

14

Documented Success Rates

20

Our Fertility Achievements

24

Awards

25

Your 1st Visit to Alpha IVF & Women’s Specialists

26

Talk to Us

27


Our Doctors


Dato’ Dr. Colin Lee Soon Soo

FRCOG (UK), MBBS (AUS], MMED (S’PORE)  Consultant Fertility Specialist & Gynaecologist  Medical Director 

 The name of Dato Dr. Colin Lee is no stranger in  the field of  fertility treatment in the international  fertility fraternity. 

 Dato’ Dr Colin Lee Soon Soo set up his new fertility  centre,  Alpha Fertility Centre, in 2011 which is now  better known as  Alpha IVF & Women’s Specialists.  He was also the founder and  medical director of  Tropicana Medical Centre, TMC Fertility Centre  and Damansara Fertility Centre. 

 Dato’ Dr. Colin Lee leads the team at Alpha IVF  & Women’s Specialists with the mission to enable  every couple to fully  realise their potential for  parenthood. 

 The core tenet of this work is reflected in  the professional  standard we are adopting  in Alpha IVF, as well as IVF success  rates that  are comparable with top IVF centres around   the world.



Alpha IVF Group’s 

International Scientific Board


  

Emeritus Professor Dr. Bruno Lunenfeld

Dr. John Keith

World-wide pioneer in the development  and deployment of human menopausal  gonadotrophins (HMG) for the treatment of  infertility (since 1961). All patients undergoing  IVF who use HMG such as Gonal-F, Puregon,  Menopur and Humog are indebted to this  towering pioneer of fertility treatment.

Co-created the world’s 1st structured training  manual for embryologists. Dr Keith also co created the world’s first professional body  for embryologists, that is, the Association of  Clinical Embryologists (ACE).

  

Emeritus Professor Dr. Alan Trounson

Dr. Michelle Perugini

Pioneered the world’s first human IVF  pregnancy (1973). He was also the first in  the world to achieve a pregnancy following  freeze thaw of embryos and pioneered early  development in cryopreservation of embryos  and blastocysts.


 Prof Dr. Alan Trounson is also a pioneer in  embryo biopsy and In-Vitro Maturation (IVM).

Co-founder & CEO of Presagen, co-created  Presagen’s first product Life Whisperer, a  suite of applications that use AI for embryo  assessment to improve pregnancy outcomes  in IVF. 


 An avid supporter of the AI and women’s  health sectors globally, and the Winner of the  2021 Women in AI (WAI) Healthcare Award.



Nurses  & Counsellors

Our fertility trained nurses will walk alongside with you and are ever ready to be your primary contact to guide and support you throughout your journey with us.




Customised 

 Fertility Treatments

 • Ovulation Induction

 • Intra Uterine Insemination (IUI)

 • In Vitro Fertilisation (IVF)

 • Intra-Cytoplasmic Sperm Injection (ICSI)

 • Preimplantation Genetic Testing (PGT) :

 • PGT-A: Aneuploidy, formerly called PGS 

(to screen all 23 pairs of chromosomes)

 • PGT-M for Monogenic disorders 

(to look for  specific disorders that you and your partner  are carriers of)

 • PGT-SR for Chromosomal Structural Rearrangement

 • PGT-HLA for definitive HLA matching

 (to look for an HLA-matched embryo for an  affected child you already have)

 • Blastocysts Transfer Programme

 • Egg / Embryo / Sperm Freezing

 • Endometrium Receptivity Analysis (ERA)

 • Endometrial Microbiome Metagenomic Analysis (EMMA)

 • Analysis of Infectious Chronic Endometritis (ALICE)

 • Savior Sibling Programme (PGT - HLA)

 • X & Y Sperm Sorting

 • Advanced Reproductive Surgery

 • General O&G

 • Ova-PRP - Ovarian Rejuvenation

 • Endo-PRP - Endometrium Rejuvenation

 • Artificial Intelligence (AI) - Enhanced Embryo Selection



3 • Embryoscope+®Time Lapse Monitoring System

As the first IVF centre in Malaysia that used time  lapse system, Alpha IF has now upgraded to  EmbryoScope+® Time Lapse System to carefully  monitor and this cutting-edge system combines  each incubator, high resolution camera and  computer software to automatically take images  of each developing embryo every 10 minutes.  These images can be reviewed at any time by our  highly trained embryologists without removing  the embryos from the incubator, hence providing  undisturbed culture conditions, and improves  embryo selection by selecting the most viable  embryo for transfer.


  


4• Blastocyst Transfer Programme


World Class Success Rate 79.5%*


Pregnancy rate from transferring a single good graded euploid blastocyst.


Good graded euploid blastocyst transfer



* Lee C.S.S., Low S.Y., Lim Y.X., Keith J (Alpha Fertility Centre). Vitrified-warmed good graded euploid blastocysts aged < 120hours at the time of transfer  yield superior clinical pregnancy and implantation rates. Presented at 24th Congress of the Obstetrical and Gynecological Society of Malaysia, 2 - 5th  June 2016, Kuala Lumpur, Malaysia




Since July 2013, Alpha IVF & Women’s Specialists  had started using a new embryo freezing and  thawing method (Cryotec Method, Japan) and it  had led us to achieve a 100% post-thaw survival  rate resulting in high clinical pregnancy rates. The  chart on the right shows the clinical outcome of  Alpha IVF & Women’s Specialists’s frozen-thawed  cycles from July 2013 to December 2015*





Donor Egg Programme


Egg donation makes pregnancy possible for women who might not otherwise be able to get pregnant  using their own eggs. Alpha IVF & Women’s Specialists has one of the best egg donation programmes in  Malaysia. Regardless of fertility history, all recipients of all ages have almost an equal chance of success.


* Leong, WY; Lee, CSS; Low SY (Alpha Fertility Centre). Oocyte donation outcome at Alpha International Fertility Centre. An International Journal of  Obstetrics & Gynaecology 2012;119(S1):PP. 137. Presented at the 10th Royal College of Obstetricians & Gynaecologists International Scientific Congress,  5-8 June 2012, Sarawak, Malaysia.



Achievements

1• Live birth in an ERA patient with a receptive endometrium at 190+/- 3   hours (Day 8) of progesterone. (Reproductive BioMedicine Online.   2022:45:51-52;13th ALPHA BIENNIAL CONFERENCE, Alpha   Conference, 6th - 9th October 2022) 

 2• Live birth following frozen embryo transfer of a blastocyst selected   using artificial intelligence (AI). (28th International Congress of the   Obstetrical & Gynaecological Society of Malaysia, 23-25 July 2021)   (South-East Asia 1st) 

 3• 100% post-warmed survival rate for 6,059 embryos in Alpha IVF. (28th   International Congress of the Obstetrical & Gynaecological Society of   Malaysia, 23-25 July 2021) 

 4• Live birth in an ERA patient with a receptive endometrium at 85+/-   hours post-progesterone. (10th Virtual Congress Asia Pacific Initiative   on Reproduction (ASPIRE),30 April-2 May 2021)   

5• Live births following day 7 blastocyst transfers at Alpha IVF. (10th    Virtual Congress Asia Pacific Initiative on Reproduction (ASPIRE), 30    April-2 May 2021) 

 6• Successful pregnancies following transfer of blastocysts derived from   delayed-intracytoplasmic sperm injection (delayed-ICSI). (36   Virtual Annual Meeting of European Society of Human Reproduction   and Embryology (ESHRE), 05-08 July 2020) 

 7• Demonstrated that blastocysts arising from Day1-Mll oocytes   have the same euploidy rate as Day0-MIl oocytes from the same   cycle and therefore should not be discarded. This will increase   the number of euploid blastocysts available for embryo transfer.   (9th Congress of Asia Pacific Initiative on Reproduction (ASPIRE),   3-5 May 2019, Central, Hong Kong.) 

 8• Demonstrated that repeated vitrification and repeated   warming procedures have no detrimental effect on blastocyst   survival and pregnancy outcome. (18th International Conference   on Preimplantation Genetic Diagnosis, Geneva, Switzerland,   2019) 

 9• Savior Sibling Programme for monogenic disorders using direct   HLA typing on the embryos from the same biopsy sample used   for PGT testing (AICOG, Bengaluru, 8-12 Jan 2019) 

 10• Demonstrated that administration of Clotrimazole prior to   Frozen Embryo Transfer [FET] Cycles may improve implantation   rate. (16th International Conference on Preimplantation Genetic   Diagnosis, Valencia, Spain, 2017) 

 11• Demonstrated that combining a Day 5 and a Day 6 Blastocyst   results in very high pregnancy rates (Clinical Pregnancy Rate:   71.4%, Implantation Rate: 46.4%). (6th Congress of the Asia   Pacitic Initiative on Reproduction, Jakarta, Indonesia, 8-10th   April 2016)

12• Successful live birth following frozen embryo transfer of a 1PN   embryo after PGD-MaCGH analysis. (14th International   Conference on PGD, Chicago, USA 2015) 

 13• Demonstrated that embryos derived from conventional IF have   lower aneuploidy rates compared to embryos derived from ICSI.   (13th International Conference on PGD. Canterbury, UK, May   2014) 

 14• Demonstrated similar euploidy rates among Day 3 OPN, 1PN   and 2PN embryos using MaCGH analysis. (12th International   Conference on PGD. Istanbul, Turkey, May 2013) 

 15• Reported successful pregnancy following the use of freeze-   thawed sperm, freeze-thawed eggs, and freeze-thawed   embryos. (10th Royal College of O&G International Scientific   Congress, June 2012) 

 16• Successful pregnancy and delivery in a patient with Mullerian   Dysgenesis la woman born without a vaginal. (Reproductive   BioMedicine Online, Vol 24, Issue 5, Pages 547-549), (May 2012] 

 17• Successful pregnancy and delivery following PGD-CGH diagnosis of   chromosome inversion with fresh transfer. (11th International   Conference on PGD, May 17th-19th 2012. Austria) 

 18• PRP treatment for Ashermann’s Syndrome with resulting successful   pregnancy and delivery. (2010) 

 19• Demonstrated that an older uterus (about 40 years old) achieves   similar pregnancy rates compared to uterus less than 30 years old.   (Reproductive Biomedicine Online, 16[SUPPI2]:S37-38 2008) 

 20• Reported delivery following the salvage of a presumably abnormal   embryo. (7th Congress of PGDIS. Melbourne, Australia 13-15 June   2007) 

 21• Developed a mathematical formula to guide doctors on appropriate   quantum of ovarian drilling. (Life, Issue 9, Page 14-16, 2007) 

 22• Demonstrated the value of tube rinsing in oocyte recovery procedure.   (14th World Congress on IVF and 3rd World Congress on IVM.   Montreal, Canada, 2007) 

 23• Demonstrated the importance of embryo transfer duration on   pregnancy outcome. (14th World Congress on IVF and 3rd World   Congress on IVM. Montreal, Canada, 2007)     • Invented a womb mimicking machine called SHOOGLE” that aims to   improve circulation of nutrients to embryos.


For list of other achievements, Please refer to our website at  .


Your 1st Visit 

to Alpha IVF & Women’s 

Specialists



Fertility Assessment


The initial crucial step in assessing your fertility potential  and concerns will usually involve a fertility assessment on  both you and your partner. 

This assessment typically involves a thorough medical  history review, physical examinations, and reproductive  function tests. By analysing factors such as sperm quality,  ovarian reserve, and reproductive anatomy, the doctor can  identify any underlying issues or potential challenges.

Tips:


Your Treatment

At Alpha IVF, we cater to your specific needs by providing a  treatment programme that is tailor-made just for you. 

Upon commencement of treatment, a combination of  prescription drugs and a complete drugs administration  sheet will be given to you. Other drugs may be introduced  in the treatment programme depending on individual  requirements.

Based on this comprehensive evaluation, the doctor  can then gain valuable insights and offer appropriate  recommendations and design a personalised treatment  plan that suits the specific needs and conditions of the  couple.










Talk to Us

Making an appointment to see a fertility specialist may seem  like a big step. Considering that there many misconceptions  associated with fertility issues, we know how difficult it is for  couples to take the first step in crossing that bridge.  Talk to us directly and see how we can help to improve your  overall experience and pregnancy outcomes. Alpha IVF has  many treatment options to help your dreams of building a  family come true.




Contact our softwar:

Telegram

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马来西亚|+60 1116592678

香港+852 65458023

北京 |19919999145

武汉 |16717120005

上海 |17027022222

郑州 |15537275551


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